Xanthine oxidase: four roles for the enzyme in rheumatoid pathology.

نویسندگان

  • D R Blake
  • C R Stevens
  • T Sahinoglu
  • G Ellis
  • K Gaffney
  • S Edmonds
  • M Benboubetra
  • R Harrison
  • S Jawed
  • J Kanczler
  • T M Millar
  • P G Winyard
  • Z Zhang
چکیده

Krebs, E. G. (1994) Trends Biochem. Sci. 19,439 Battelli, M. G., Lorenzoni, E. and Stirpe, F. (1973) Biochem. J. 131, 191-198 Parks, D. A., Granger, D. N., Bulkley, G. B. and Shah, A. K. (1985) Gastroenterology 89, 6-12 Miller, L. S., Morita, Y., Rangan, U., Kondo, S., Clemens, M. G. and Bulkley, G. B. (1996) Int. J. Microcirc. 16, 147-154 Morita, Y., Clemens, M. G., Miller, L. S., Rangan, U., Kondo, S., Miyasaka, M., Yoshikawa, T. and Bulkley, G. B. (1995) Am. J. Physiol. 269,

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Virtual Screening Analysis and In-vitro Xanthine Oxidase Inhibitory Activity of Some Commercially Available Flavonoids

Allopurinol, the xanthine oxidase inhibitor, is the only drug available for the treatment of gout. We examined the xanthine oxidase inhibitory activity of some commercially available flavonoids such asepigallocatechin, acacatechin, myricetin, naringenin, daidzein and glycitein by virtual screening and in-vitro studies. The interacting residues within the complex model and their contact types we...

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Onion, a Potent Inhibitor of Xantine Oxidase

Onion (Allium Cepa) contains high levels of flavonoids. Although there are many studies indicating the inhibitory effects of flavonoids on xanthine oxidase, there is no report on the effect of onion on this enzyme. Therefore, in the present study, the inhibitory effects of onion on xanthine oxidase are investigated. Fresh filtered juice of onion was prepared and its inhibitory effect on guine...

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 25 3  شماره 

صفحات  -

تاریخ انتشار 1997